STUDY ON SYNTHESIS OF SOME THIOUREA DERIVATIES CONTAINING THIAZOLE SCAFFOLD USING MICROWAVE OVEN.

Thiourea and its derivatives represent a well-known important group of organic compound due to their diverse application in fields such as medicine, agriculture, coordination, and analytical chemistry [1,4]...In the present study, phenyl isothiocyanate and aromatic amines were milled in a porcelain crucible with lid and irradiated by using the MW irradiation power of 120W in several minutesto give the corresponding thioureas in high yields. Their biological activities were evaluated. They are screened for anti-bacterial activity against Escherichia coli and Staphylococcus aureus as well as screened for antifungal activity by agar diffusion method at 1 µg/ mL concentration in DMSO [2]... All the Structures of compounds were indentified by IR, 1H-NMR,13C-NMR spectra.