Search Result

Background: Chronic kidney disease (CKD) is a major public health concern, particularly in aging populations. Physiological aging is associated with a progressive decline in renal function, exacerbated by nutritional imbalances such as hypoproteinemia. In resource-limited settings, where access to a balanced diet and healthcare services is restricted, these factors become critical for CKD prevention. This study aims to demonstrate how the interaction between advanced age and hypoproteinemia contributes to the deterioration of glomerular filtration rate (GFR) across various regions in Cameroon. Objective: To analyze the synergistic effect of aging and hypoproteinemia on renal function in five localities of Western Cameroon, identifying high-risk populations and proposing targeted recommendations. Methods: A cross-sectional study was conducted on a representative sample of 768 adults aged 50 and above, categorized into four age groups (50–59, 60–69, 70–79, and ?80 years). Renal function was assessed using the MDRD equation to estimate GFR, and total protein levels were measured via spectrophotometry. Statistical analysis focused on correlations between age, plasma protein levels, and CKD prevalence across different localities. Results: The findings revealed a significant relationship between aging, hypoproteinemia, and renal function decline. CKD prevalence increased exponentially in individuals over 60 years, with higher rates observed in the Dschang and Baham localities. Additionally, hypoproteinemia was identified as an independent aggravating factor, increasing the risk of renal dysfunction by 2.3 times (95% CI: 1.8–2.9). Conclusions: These results underscore the need for enhanced nutritional and nephrological surveillance among elderly populations, particularly in regions with high malnutrition prevalence. A combined approach integrating nutritional strategies and early monitoring of renal biomarkers could help mitigate the CKD burden in these vulnerable populations.

Objectives: This study aims to examine the relationship between obesity, hypertension, and aging in individuals aged 50 years and above in the West Cameroon region. Methods: A total of 768 participants aged 50 and above were included in the study, recruited from five localities in West Cameroon (Bafang, Bafoussam, Baham, Bandjoun, and Dschang). Blood pressure was measured using a sphygmomanometer, and body mass index (BMI) was calculated. Obesity was classified according to the World Health Organization (WHO) criteria, and systolic blood pressure was categorized into seven levels ranging from optimal to severe hypertension. The data were analyzed to assess the correlations between age, sex, locality, and these two risk factors. Results: A total of 22.5% of participants had optimal systolic blood pressure, while 22.4% presented mild hypertension. Women over the age of 70 were the most affected by moderate obesity (17.2%) and severe obesity (33.3%). Severe hypertension was more prevalent in Dschang and Bandjoun, particularly among individuals suffering from obesity. Conclusion: The findings highlight a significant correlation between obesity, hypertension, and aging, underscoring the need for increased monitoring and targeted interventions. Proactive management of obesity and hypertension is essential to prevent cardiovascular complications in the aging population of this region.