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This research was guided to investigate the effects of supplementation of DL-methionine (DLM) and liquid DL-methionine hydroxy analog free acid (MHA) in diets on productive performance, hematological, blood metabolites and histological parameters in broiler chickens under summer conditions in Sina. A total number of 180 one day old Hubbard broiler chicks, with initial body weight (46.9 ± 2.5 g), were divided into 6 equal treatment groups. The treatment were DL-methionine (DLM) at 0.25% level, acid liquid methionine (ALM) and methionine hydroxyl analogue Ca salt (MHA) at 0.29 and 0.30%, respectively with and without dietary L-Threonine (0.0 and 1.0 g/kg diet). Chicks were raised for 35 days in battery cages under semi – arid conditions (high ambient temperature and relative humidity) in open-side housing. The obtained results indicate: The productive performance of DLM and MHA were not significantly different. Supplementation of DLM and MHA significantly improved final body weight, body weight gain, average daily gain, and feed conversion ratio when compared to the control group (P<0.01). The use of DLM enhanced the plasma methionine concentration (P<0.01) and increased the heterophil/lymphocyte ratio (P<0.05). While MHA elevated the plasma urea and uric acid concentration levels (P<0.05).

Before the development of modern medicine, people relied on medicinal plants to treat and manage illnesses. For a huge portion of people, mainly in the poor countries, medicinal herbs continue to offer excellent health protection. Date palm is a delicious, powerfully nutritious, aphrodisiac, tonic, and laxative fruit enjoyed by all since ancient times dates are seen to be an ideal food and part of a balanced diet because of the vital nutritional information included in them. Dates are not only able to increase haemoglobin levels, but also increase other haematological parameters, such as: ferritin levels, haematocrit, serum iron and transferrin saturation.

The toxicity of heavy metals when their concentration exceeds allowable limits has made their presence in our environment of great concern. These metals are released into the environment through a range of sources, including industrial processes into nearby rivers thereby polluting the river for domesticated usage. Thirty-six male, healthy rats (Rattus novergicus) were purchased from the Animal House and given water samples from the Asa River in different concentrations (20, 40, 60, 80, and 100%). Rats from the experimental and control groups were sacrificed and the liver and kidney were removed, washed in 10% formal saline, and prepared for histomorphological examinations. Rats\' blood was also taken for haematological and biochemical indices during the animal sacrifice processess. In this study, Alanine amino transferase (ALT )and Aspartate amino transferase (AST) levels at higher concentrations were significantly noted when compared to the control group resulting to alteration of the liver and kidney organs at higher concentrations with mild periportal cellular infiltration and mild congestion of the renal interstitium and severe congestion and hemorrhage at the renal interstitium, respectively. Rats\' haematological and biochemical indices did not differ significantly from the control group.