Emmanuel Ifeanyi Obeagu, Chioma Ibe, Getrude Uzoma Obeagu, Chinyere Nkemjika Anyanwu and Ebere Emilia Ayogu
The management of Human Immunodeficiency Virus (HIV) necessitates a nuanced comprehension of immune responses, with the CD4/CD8 ratio emerging as a pivotal parameter in this regard. This review investigates the clinical implications of CD4/CD8 ratios in HIV, encompassing their role as prognostic markers, treatment monitoring tools, and indicators of immunological reconstitution during antiretroviral therapy. We explore the baseline CD4/CD8 ratio in healthy individuals, scrutinize its prognostic significance in HIV progression, and assess its dynamic changes throughout treatment. Additionally, the article addresses challenges, controversies, and future directions in CD4/CD8 ratio research, offering a comprehensive overview of its potential as a key immunological marker in the ongoing battle against HIV.
Download PDF
View Abstract
No. of Downloads: 1 |
No. of Views: 5
