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Malaria is the most common protozoan infection and is one of the major public health problems in developing nations like Nepal. This study was conducted to find out total number of malaria cases in BPKIHS from 2006 to 2015 AD and to know the duration for which cases were admitted and improvement seen in them. This is a hospital based retrospective study conducted from 27th November to 10thDecember to see the number of malaria cases in B P Koirala Institute of Health Sciences, Dharan of Nepal, a tertiary level referral hospital in the Eastern Nepal. It was study in which secondary data, consistent with the diagnosis of malaria was collected from the Medical Record Section of BPKIHS and reviewed. Five hundred fifty four cases of malaria were enrolled. The patients were predominantly males (nearly 61.2%) and it was more commonly seen in 1-20 years age group (40.8%). Most of the cases were from Jhapa (22%), Sunsari (19.5%) and Morang (17.3%) District respectively. Most of the patients (69.9%) were admitted in Medicine wards. Almost 83.9% of admitted malaria cases were improved in BPKIHS.There seems to be decreasing number of cases since 2010 but still there is burden of malaria cases. We conclude that the problem of malaria is common and has become a key public health concern for all.