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Alcoholism, also known as alcohol use disorder, is a condition in which a person has a desire or physical need to consume alcohol, and impaired ability to stop or control alcohol use despite adverse social, occupational, or health consequences.” Alcoholism mainly damages important organs like liver, heart and brain. Many psychological illnesses like dementia, anxiety and depression are caused by alcohol addiction. More over Alcoholism poses extra financial burden and affects quality of life. Hence it is important to treat the alcohol dependence to reduce or stop alcohol consumption by the addicted individual. Considering the need of safe medication for alcohol de-addiction, A clinical Trial was conducted on a Poly herbal combination Wesnil Plus to evaluate its effect for alcohol de addiction. Statistically significant improvement was seen on Alcohol withdrawal scale in the treated patients and the craving and frequency of alcohol consumption was significantly reduced.