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Major sources of increase in air pollutant concentration in the ambient air are due to rapid industrialization and urbanization along with the growth in emission from automobiles. In the present study ambient air quality has been monitored for Oxides of Nitrogen (NOx), Sulphur dioxide (SO2), Particulate Matters - PM10 and PM2.5 by considering a typical rubber reclamation Plant, Mysuru as a source of emission. ISCST3 an air pollutant dispersion model has been used to predict the dispersion of air pollutant concentrations such as, NOx, SO2, and PM10. The monitoring of ambient air was revealed that, at JSS Urban Haat, the PM10 and PM2.5 concentrations were found to be 60 µg/m3 and 30 µg/m3, respectively. The maximum PM10 and PM2.5 concentration was observed at JSS urban Haat (R4). The lowest concentration of PM10 and PM2.5 of 50 µg/m3 and 19 µg/m3 was noticed at Health Care Centre (R2) and Dexter Logistics (R3), respectively. Results of ISCST3 dispersion model run showed maximum PM10 of 0.12634 µg/m3 was observed at JSS Urban Haat and maximum SO2 concentration was found to be of 0.0618 µg/m3 at Health Care Centre. Further, predicted concentrations were found to be less than the observed concentrations, which may be due to the fact that, the model prediction considered the emissions from two stacks of rubber reclamation industrial Plant, and not being considered from other industrial emissions as well as automobiles.

Some epidemiological studies have reported a relationship between thyroid dysfunctions and the risk of breast cancer’s giving the similarities between estrogen and thyroid function. This study was therefore aimed at evaluating the level of thyroid gland hormones, TSH and estrogen in breast cancer patients. A cross-sectional study was carried out in the month of September to November 2019. A total of 60 subjects attending breast cancer screening clinic of Federal Medical Center and Imo State University, Owerri were recruited for this study. The 60 subjects are between the ages of 20-60 years. The 60 subjects were divided into two groups: Group 1 (Test) consists of 30 females with breast cancer. Group 2 (Control) consists of 30 apparently healthy women with no breast cancer. Blood samples were collected, and the level of thyroid hormone and estrogen was determined. Data generated was then analysed using SPSS version 21. There was no significant difference (p=0.308 and p=0.626 respectively) in the mean value of T3 and T4 in breast cancer patients (3.42±0.07 and 1.41±0.15 respectively)µIU/ml when compared to Controls (3.11±0.64 and 1.35±0.23)µIU/ml. The mean value of TSH was significantly increased (p=0.02) in breast cancer patients (2.79±1.05)Pmol/ml when compared to controls (1.40±0.17)Pmol/ml. The mean value of estrogen was significantly increased (p=0.000) in breast cancer patients (540.39±66.70)pg/ml when compared to controls (222.10±58.09)pg/ml. There was a non significant negative correlation of serum estrogen with serum T3, and T4, (r= -0.253, p=0.682 and r=-0.107, p=0.864). There was a non significant positive correlation of serum estrogen with serum TSH (r=0.380, p=0.528). There is a strong association between breast cancer and serum concentrations of thyroid stimulating hormone and estrogen, but there is no alteration in TSH hormones in breast cancer.