G. D. Gujar and A. A. Attarwala.
There is a growing concern globally over issues such as global warming, climate change etc. Various factors that affect the environment have now come into focus, air pollution, water pollution and soil pollution becoming the priority. While activities such as combustion of fuel, ineffective sewage treatment, and deforestation have been the primary cause of concern, we cannot overlook the effect the chemicals and pharmaceuticals have on the environment. Though there are no regulatory standards set for the levels of pharmaceutical products and by-products that can be found in the environment, it is high time that the Governments and the industry take note of the adverse effects that the pharmaceuticals are having on the environment. This paper aims to study the harmful and unwanted effects of drugs on various elements such as water, air, soil and public health.
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Esther Ugo Alum, Emmanuel Ifeanyi Obeagu, Okechukwu P.C. Ugwu, Obasi Uche Orji, Adeyinka O. Adepoju, Mariam O. Amusa and Nzubechukwu Edwin
Breast cancer, characterized by uncontrollable growth of abnormal breast cells forming tumors, can be fatal if unchecked, spreading throughout the body. Originating in breast milk ducts or lobules, its early stages pose no immediate threat, but invasive forms can metastasize to other organs. Its prevalence has surpassed lung cancer globally. Projections suggest 28.4 million cases by 2040. Treatment varies based on the individual, cancer type, and its spread, involving surgery, radiation, and medication. Natural plant products show promise as antitumor and anti-cancer agents, exhibiting reduced toxicity and resistance to conventional drugs. These products leverage antioxidant, anti-inflammatory, and immunomodulatory properties, influencing cancer cell behavior. Some studies highlight herbs\' potential in developing anti-cancer drugs. Notably, breast cancer\'s impact is significant in developing countries. Inadequate medical infrastructure and high treatment costs promote the use of natural products in these countries. Plant-based remedies offer a less toxic alternative, crucial in regions with limited access to conventional treatments. Understanding breast cancer and early diagnosis is critical in managing its impact. Therefore, this review delves into breast cancer intricacies and underscores natural plant products\' potential in mitigating the projected increase in breast cancer-related deaths.
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K. Malleswari, Dr. D. Rama Brahma Reddy, T. Blessi, G. Suvarna and B. Sri Lakshmi
Over the years, researchers have attempted to improve the potency of medicament utilization for the treatment of a variety of diseases. Drug targeting is a phenomenon in which a drug is distributed in the body in such a way that it interacts with the target tissue at a cellular or sub-cellular level to achieve a desired therapeutic response at the desired site while avoiding unwanted interactions at other sites. This can be accomplished using modern drug delivery system targeting methods such as niosomes. Niosomes are a novel drug delivery system that encapsulates the medication in a vesicle. The vesicle is made up of a non-ionic surfactant bilayer. The particle size of the niosome must be in the range of 10 nm -100 nm. Niosomes are preferred over liposomes because they are more stable and less expensive. Niosomes enhance the pharmacological action of drug molecules by delaying the drug\'s clearance from circulation, protecting the drug from the biological environment, and limiting the effects to the target cells. It has applications in cancer treatment, as a carrier in hemoglobin, delivery of peptide drugs via the oral route, treatment of leishmaniasis, ophthalmic delivery, and as a carrier in dermal drug delivery. This review article focuses on the vesicular system\'s composition, benefits, types of niosomes, methods of preparation, characterization, and application.
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