Esther Ugo Alum, Okechukwu P. C. Ugwu, Emmanuel Ifeanyi Obeagu, Patrick Maduabuchi Aja, Michael Ben Okon and Daniel Ejim Uti
The human immunodeficiency virus (HIV) infection is one of the health burdens ravaging the world with severe impact in developing regions. Women and young girls are more threatened by HIV infection than their male counterparts. Notably, in 2022, 63% of all new HIV infections were attributed to women in sub-Saharan Africa. The anatomical architecture of the female genital tracts, poverty, gender imbalance, unrefined cultural norms aimed at subjugating women, early exposure to sex and marriage, and illiteracy are fingered to contribute to the increased risk of HIV infection in women and young girls. Mitigating these factors will no doubt help curb the prevalence of HIV infection. Herein, we highlighted some measures that could help turn down women’s risk of getting HIV including abstinence, regular use of condoms, delay in sexual exposure, maintaining one faithful partner, timely voluntary counseling and testing, formal education, monitoring of alcohol use, proper dieting, and scrapping of cultural norms targeted at subjugating women. Successfully turning down HIV infection risk in women and young girls will be a breakthrough in the combat against HIV infection since women and young girls being the most vulnerable group must have been salvaged. This paper reviewed the prevalence of HIV/AIDS in women and young girls, the factors fueling the high prevalence, and enumerated key areas to target in order to minimize this menace. Related published data from various databases were utilized.
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Esther Ugo Alum, Emmanuel Ifeanyi Obeagu, Okechukwu P.C. Ugwu, Obasi Uche Orji, Adeyinka O. Adepoju, Mariam O. Amusa and Nzubechukwu Edwin
Breast cancer, characterized by uncontrollable growth of abnormal breast cells forming tumors, can be fatal if unchecked, spreading throughout the body. Originating in breast milk ducts or lobules, its early stages pose no immediate threat, but invasive forms can metastasize to other organs. Its prevalence has surpassed lung cancer globally. Projections suggest 28.4 million cases by 2040. Treatment varies based on the individual, cancer type, and its spread, involving surgery, radiation, and medication. Natural plant products show promise as antitumor and anti-cancer agents, exhibiting reduced toxicity and resistance to conventional drugs. These products leverage antioxidant, anti-inflammatory, and immunomodulatory properties, influencing cancer cell behavior. Some studies highlight herbs\' potential in developing anti-cancer drugs. Notably, breast cancer\'s impact is significant in developing countries. Inadequate medical infrastructure and high treatment costs promote the use of natural products in these countries. Plant-based remedies offer a less toxic alternative, crucial in regions with limited access to conventional treatments. Understanding breast cancer and early diagnosis is critical in managing its impact. Therefore, this review delves into breast cancer intricacies and underscores natural plant products\' potential in mitigating the projected increase in breast cancer-related deaths.
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Esther Ugo Alum, Okechukwu P. C. Ugwu, Emmanuel Ifeanyi Obeagu, Obasi Uche Orji, Nzubechukwu Edwin and Michael Ben Okon
Exclusive breastfeeding (EBF)during a baby\'s first six months of life is still a vital worldwide public health approach that UNICEF and the World Health Organization (WHO) support. The numerous advantages of early brain feeding (EBF) include decreased rates of morbidity and mortality in children, healthcare cost savings, improved mother-child bonding, and decreased risks of a variety of childhood illnesses. Nevertheless, the global incidence of EBF is below desired levels, especially in East Africa, despite these well-established benefits. The present publication provides a complete review of exclusive breastfeeding practices in East Africa, focusing on mom knowledge, attitudes, and practices. Research indicates notable deficiencies in mothers\' comprehension and compliance with EBF guidelines within the area. While there are several obstacles to optimum breastfeeding practices, including cultural views, HIV worries, a lack of awareness, and societal influences, interventions such as counseling and educational campaigns have not demonstrated much success, especially when it comes to young moms. The article also investigates the possible function of religious authorities as powerful proponents of exclusive breastfeeding. Considering the significant impact that religious leaders have on East African communities, enlisting their support seems to be a viable way to improve EBF practices and close current gaps. Using the power of religious leaders in conjunction with current initiatives may be a crucial way to promote and maintain the best possible breastfeeding practices, which would eventually improve the health and well-being of infants in the area.
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Esther Ugo Alum, Okechukwu P.C. Ugwu, Emmanuel Ifeanyi Obeagu, Patrick Maduabuchi Aja, Chinyere Nneoma Ugwu and Michael Ben Okon
Diabetes mellitus, indicated by increased levels of blood sugar stemming from inadequate insulin synthesis or poor usage, presents a persistent metabolic challenge. Nutrition stands as a critical pillar in managing diabetes, emphasizing a balanced diet with controlled carbohydrate intake and whole-food emphasis. Yet, implementing nutritional strategies tailored to individual needs remains challenging due to diverse dietary information and evolving science. Though consensus on optimal nutritional therapy lacks uniformity, fundamental dietary principles persist across diabetes types. Studies have shown the effectiveness of nutritional interventions in managing other health conditions, underscoring the need to enhance care for individuals with diabetes. This manuscript delves into the comprehensive landscape of nutritional guidelines for diabetes management, addressing macronutrients\' roles, micronutrient significance, herbal supplements, dietary fiber, glycemic index/load comprehension, and the pivotal role of nutritional counseling. It highlights the importance of tailored dietary plans, focusing on carbohydrates, proteins, and fats, while also elucidating the crucial role of micronutrients such as magnesium, zinc, chromium, and vitamins in diabetes care. Additionally, it examines the potential benefits and caution around herbal supplements in diabetes management. This manuscript provides a holistic exploration of nutritional strategies, emphasizing the need for personalized approaches and comprehensive support systems to optimize diabetes care and overall well-being.
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Esther Ugo Alum, Emmanuel Ifeanyi Obeagu, Okechukwu P. C. Ugwu, Chinyere Nneoma Ugwu, Daniel Ejim Uti, Awotunde O. Samson and Dorcas Ibukun Akinloye
Pregnancy demands unique nutritional necessities different from those of women who are not pregnant, involving vital roles of vitamins, minerals, and omega-3 fatty acids. These elements are pivotal for the progression of a healthy pregnancy, aiding mothers in coping with common discomforts and averting complications. Presently, supplementation recommendations for pregnant women vary across nations, prompting the need for comprehensive nutrition counseling as a pivotal aspect of prenatal care. The state of a woman\'s nutrition has a major effect on her health, the course of her pregnancy, and the welfare of her fetus and newborn. Providers of healthcare must recognize and address these distinctive nutritional requisites, advocating for tailored counseling that considers diverse factors such as availability of food, social, ethnic background, cultural dietary selections, and body mass index. Adjustments become imperative in instances of pregnancy complications like gestational diabetes. Collaboration with nutritionists or registered dietitians is instrumental in delivering effective dietary interventions. This review underscores the benefits and current guidelines for mineral, vitamin, and omega-3 fatty acid intake during pregnancy while cautioning against the adverse effects of excessive nutrient consumption and advocating for consistent nutritional guidance.
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Emmanuel Ifeanyi Obeagu, Esther Ugo Alum, Getrude Uzoma Obeagu and Okechukwu P.C. Ugwu
Sickle cell anemia (SCA) stands as a paradigm of the intricate interplay between genetic predisposition, environmental influences, and lifestyle factors shaping the complexity of this hemoglobinopathy. This comprehensive review endeavors to elucidate the multifaceted relationship between genetic determinants, environmental triggers, and individual lifestyle choices in the genesis, progression, and management of SCA. Genetically, SCA is rooted in mutations within the HBB gene, culminating in the production of aberrant hemoglobin and the characteristic sickled erythrocytes. This section scrutinizes the myriad of genetic variations, emphasizing their implications in disease severity and phenotypic diversity. The review further navigates the landscape of genetic modifiers, exploring their nuanced influence on disease manifestation among carriers of the sickle cell trait. Environmental determinants play a pivotal role in modulating the clinical course of SCA. Geographical disparities, climatic variations, prevalence of infections, and socio-economic factors intricately intertwine to influence disease prevalence, complications, and healthcare accessibility. This review meticulously examines the multifaceted impact of these environmental factors on the disease landscape. Moreover, lifestyle choices wield substantial influence over disease management and outcomes. Balanced nutrition, hydration, physical activity, and psychosocial well-being significantly impact disease severity and crisis occurrence. This section delves into the effects of lifestyle modifications, elucidating their role in minimizing complications and enhancing the quality of life for individuals navigating the challenges of SCA. This paper underscores the synergistic interplay of genetics, environmental influences, and lifestyle factors in sculpting the multifaceted nature of sickle cell anemia. Recognizing these intricate interactions provides a holistic framework for devising personalized management strategies and therapeutic interventions. The synthesis of these elements emphasizes the necessity of a comprehensive approach in unraveling the complexities of SCA and advancing tailored care for affected individuals.
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